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연구 / 개발 파이프라인 현황 - 논문 (1/2)                                                                                                                                             Appendix









             No               적응증 (Indications)                                                                 논문명(Thesis titles)



                                                                                   Anti-inflammatory Effect of Heat-killed Enterococcus faecalis EF-2001, Journal of Lifer Science, 2018

               1                       항염증                                   Enterococcus faecalis EF-2001 protects DNBS induced inflammatory bowel disease in mice model, PLOS ONE, 2019
                                                                                    Enterococcus faecalis EF-2001 유산균 사균체 첨가 발효유의 항염증 효과, J. Dairy Sci. Biotechnol., 2020

                                                                                         Protection of mice from oral candidiasis by Heat-killed Enterococcus faecalis,
                                                                                     possibly through its direct binding to Candida albicans, Medical Mycology Journal. 2014
               2                       칸디다
                                                                                                 Evaluation of the effect of a heat-killed lactic acid bacterium,
                                                                                           Enterococcus faecalis 2001, on oral candidiasis, Beneficial Microbes, 2019
                                                                   Heat-killed and Live Enterococcus faecalis Attenuates Enlarged Prostate in an Animal Model of Benign Prostatic Hyperplasia, JMB
               3                     전립선비대증
                                                                                                     (Journal of Microbiology and Biotechnology , 2021)


                                                                  Effect of Heat-Killed Enterococcus faecalis, EF-2001 on C2C12 Myoblast Damage Induced by Oxidative Stress and Muscle Volume
               4                    근위축 / 근감소
                                                                                        Decreased by Sciatic Denervation in C57BL/6 Mice, Journal of Life Science, 2019
                                                                               Heat-killed Enterococcus faecalis EF-2001 attenuates lipid accumulation in diet-induced obese(DIO)
                                                                                                   mice by activating AMPK signaling in liver, Foods, 2022
               5                        비만
                                                                              Heat-killed Enterococcus faecalis prevents adipogenesis and high fat diet-induced obesity by inhibition
                                                                           of lipid accumulation through inhibiting C/EBP-α and PPAR-γ in the Insulin Signaling Pathway, Nutrients, 2022
                                                                   Effect of heat-killed Enterococcus faecalis EF-2001 on ethanol-induced acute gastric injury in mice: Protective effect of EF-2001 on
               6                 알코올성 위염 / 위궤양
                                                                                                acute gastric ulcer, Journal of Psychiatric Research, HET, 2019


                                                                     Heat-killed Enterococcus faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice,
               7                      탈모 예방
                                                                                                      International Journal of Molecular Sciences, 2022
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